Obesity is a global problem that can be caused by many things, and it’s becoming more common. It’s estimated that almost half of the people in the US will be obese by 2030. As more people struggle with weight management and related health issues, finding an effective solution is more important than ever.

If you are finding it difficult to shed those extra pounds and a lifestyle change hasn’t helped, you might want to think about giving the Semaglutide weight loss therapy a shot. It’s an FDA-approved treatment gaining attention for its potential to help individuals achieve long-term weight loss.

Semaglutide is creating a lot of buzz in the weight loss world, and for a good reason. Even though it got approved by the U.S. Drug Administration in 2021, it’s still a big deal today.

If you haven’t heard of it before, don’t worry!

In this blog, we’ll discuss Semaglutide in length, exploring how it works, what you can expect from the program, and why it’s becoming a go-to choice for so many.

 

What is Semaglutide?

 

Semaglutide, a medication that was first developed to treat type-2 diabetes, has recently become popular as a weight loss medication.

It mimics a hormone called GLP-1 (glucagon-like peptide-1) that hits brain areas that regulate appetite. In essence, Semaglutide lowers hunger and slows digestion so that you consume fewer calories and cut weight.

The US FDA approved semaglutide in 2021 for chronic weight management under the brand name Ozempic. Several clinical trials have shown impressive results, and this approval was granted.

One major study found that participants who took Semaglutide lost, on average, 15 percent of their body weight over 104 weeks, a much more significant change than those on a placebo. It’s also one of the most effective weight loss therapies on the market right now.

FDA approval represented a big step forward for people seeking medical solutions to help them achieve their body weight loss goals — particularly for those with obesity or weight-related conditions like hypertension or high cholesterol.

If you’ve tried things like diet and exercise to drop weight, but nothing has worked, Semaglutide could be a powerful tool to consider. It may provide hope for sustained long-term weight loss results.

However, when there’s more GLP-1 in your body, your brain makes you feel less hungry and more satisfied. When combined with eating better and moving more, this can help you lose pounds and decrease your chances of getting cancer, diabetes, or heart problems, especially if you’re carrying extra weight.

 

How Semaglutide works?

 

Semaglutide works in a pretty unique way, and its effects aren’t just about reducing your hunger. It is a GLP-1 receptor agonist, meaning it copies the action of a natural hormone in your body (glucagon-like peptide-1, or GLP-1) that helps control appetite, digestion, and blood sugar levels.

GLP-1 naturally gets released into your body when you eat, telling your brain that you’re full and it’s time to stop eating. But Semaglutide goes a step further by dramatically increasing the GLP-1 signal, making you feel fuller for longer. It means that you’ll feel less hungry and, therefore, eat fewer calories.

But that’s not all. In addition, Semaglutide also slows how fast food leaves your stomach. In other words, it increases “gastric emptying time” as well. So, when you are on Semaglutide, you are full for a lot longer because the food stays in your stomach longer.

This delayed gastric emptying also reduces overall food intake without that feeling of never being full or craving food—a typical downside of most weight loss programs.

Another great advantage is that Semaglutide controls your blood sugar levels. For people with type 2 diabetes, it can considerably lower blood sugar levels. It does so by stimulating the production of insulin in your body.

This blood sugar stabilization keeps your blood glucose levels stable throughout the day, avoiding blood sugar crashes. You’ll have fewer cravings for high-sugar, high-calorie foods.

Another reason Semaglutide is so effective is that it works directly with the brain’s reward centers. These areas are responsible for those urges to snack mindlessly or indulge in cravings. Semaglutide helps to blunt this drive so you can stay on track and keep a healthy diet.

 

Is Semaglutide effective for weight loss in non-diabetics?

The short answer is yes! Semaglutide was initially created to help manage type 2 diabetes, but much research indicates it is as effective, if not more so, for weight loss in people without diabetes.

In fact, most of the clinical trials that resulted in FDA approval for weight management were done in non-diabetic subjects. One major trial, known as the STEP program, looked at the impact of Semaglutide on overweight and obese people without diabetes.

Semaglutide was groundbreaking in initial trials. In one study, subjects lost nearly 15% weight in just 68 weeks. In some cases, people even lost 20% of their starting weight. That’s a big deal in the world of weight loss medications, which have mostly produced modest reductions in weight.

This effectiveness in nondiabetics is due to Semaglutide’s interaction with the brain and digestive system. Its appetite-suppressing and gastric emptying slowing abilities also make it an equally powerful tool for those just looking to lose weight.

It is basically the way to trick your brain into feeling full with smaller portions and ultimately reduce the constant craving for food, which is a game changer for many.

What’s more interesting is that Semaglutide doesn’t just cause short-term weight loss. Studies show that people using Semaglutide are likelier to keep their body weight off. 

In fact, many of those participating in long-term trials kept their weight loss for over a year, which is a remarkable feat given the tendency to regain weight loss.

 

Benefits of Semaglutide for weight loss

Semaglutide has several benefits for weight loss. Here are some of the most pertinent ones:

 

Improves metabolic health

One of the standout benefits of Semaglutide is that it will help you lose weight and improve your overall metabolic health. Semaglutide lowers the risk of developing type 2 diabetes, a significant concern for those with obesity, by enhancing your body’s response to insulin and better blood sugar control.

In addition, it can manage inflammation in your body, which is mainly associated with different metabolic diseases. That’s on top of helping to lower cholesterol levels. And that’s a win-win because you’re losing weight while also improving your internal health.

 

Helps you lose weight slowly and safely

Often, weight loss can be a double-edged sword, with quick fixes that come with health risks. Semaglutide is different from other weight loss drugs in that it helps you shed body weight gradually and safely.

It tries to decrease the sum of calories you take in by allowing you to eat less and feel fuller. It’s easier to keep to a lower-calorie diet without always being hungry. It also helps your body store less fat, leading to a steady, slow weight loss.

Semaglutide doesn’t just help you lose body weight; it does so in a way that sets you up to succeed in the long term and be well.

 

Improves glycemic control

People don’t often think about how blood sugar levels affect their cravings and energy levels when it comes to weight management. Semaglutide really shines in this area by improving your glycemic control. Your blood glucose level is maintained under control when you are on Semaglutide. 

It helps your body to release more insulin and less glucagon, a hormone that raises blood sugar. Cravings for high-calorie, sugar foods are reduced, and your energy levels are steadier throughout the day.

 

Reduces cardiovascular risk factors

Excess weight, especially if it has been carried for a long time, can greatly increase your risk of heart disease. Luckily, Semaglutide also helps reduce cardiovascular risk factors. Semaglutide can help improve your heart health and how your body processes insulin.

 

Helps in weight loss maintenance

Keeping the weight off once it’s gone is one of the trickiest parts of any weight loss journey. Semaglutide studies have shown that it can help people maintain their weight loss for a longer period than other programs where the weight comes back.

It helps in weight management by supporting your metabolic health by reducing your appetite, a solution that can last beyond the start of treatment.

Also read: Ozempic’s Effects on Your Brain: A Personal Exploration.

 

Who should take Semaglutide for weight loss?

 

If you’re considering weight loss treatment, it’s important to know if the Semaglutide weight loss program is right for you. This medication can be life-changing, but it’s not a one-size-fits-all solution.

So, let’s see who should take Semaglutide for body weight loss and why it could be a good choice for some people.

 

People with a BMI of 30 or more

Semaglutide is specially designed for people who are obese (BMI over 30). The CDC says that a BMI of 30 or higher puts you at risk for obesity-related health problems, including heart disease, diabetes, and some cancers.

Semaglutide slows the rate of body weight regain and helps you shed weight gradually and sustainably. Studies have found that people with a BMI greater than 30 lost an average of 15 percent of their body weight over one year while taking Semaglutide with lifestyle changes.

If you’re in this category and tried other methods without success, Semaglutide may be the extra help you need to reach your health and weight goals.

 

People with a BMI of 27+ and weight-related conditions

You may also be a candidate for Semaglutide if you have other weight-related health conditions and your BMI is between 27 and 29.9.

That can mean type 2 diabetes, high blood pressure (hypertension), or high cholesterol. These conditions put you at risk for heart disease, and losing weight is often a crucial part of controlling or even reversing these health issues.

If you fall into this category, semaglutide is a game-changer. It has been shown to help control blood sugar levels and also improve cardiovascular markers such as cholesterol and blood pressure, so it is a dual-benefit medication.

 

People who are struggling with obesity-related health risks

If you’ve been struggling with obesity and the health risks that come with it, Semaglutide may be the extra help you need to get your health back in order.

Some of the complications that come with obesity include sleep apnea, fatty liver disease, joint problems, and a few forms of cancer. It can drastically reduce your risk of these conditions by reducing your weight.

Semaglutide addresses these issues by modulating different pathways. It helps regulate appetite, control blood sugar, and improve overall body metabolism.

 

People looking for a medical solution after other methods have failed

Traditional weight loss techniques such as low-calorie diet and exercise aren’t for everyone. Semaglutide might be the solution you’ve been looking for if you’ve already been down the fad diet and intense workout program path and haven’t seen lasting results yet.

It’s no secret that many people have trouble with appetite control, cravings, or metabolic issues that make losing weight seem impossible. Semaglutide helps you take control of your weight in a manageable way because it addresses these underlying issues.

Semaglutide is effective, of course, but it’s not a magic bullet. However,  when combined with healthy lifestyle changes, it works best. But for people who’ve struggled to lose weight through a reduced-calorie diet and exercise on their own, Semaglutide can be a helpful supplement to help you reach and maintain a healthy weight.

At LA ViE MD, we would love to help you get started on Semaglutide therapy. Our experienced staff will answer all your questions and concerns and help you throughout your weight loss journey. Book an appointment with us today! 

 

Who should avoid taking semaglutide for weight loss?

 

While Semaglutide is effective for many, it’s not for everyone. Some people should not take this medication because of the potential risks or because of other health problems.

If you’re considering Semaglutide, it’s essential to know if any of these situations apply to you: 

 

Those with a history of medullary thyroid cancer

Semaglutide may not be a safe option for you if you or a close family member has a history of medullary thyroid carcinoma (MTC).

The reason for this is that animal studies have shown that Semaglutide and other GLP-1 receptor agonists increase the risk of thyroid tumors. These findings haven’t been confirmed in humans, but doctors advise against taking it if you have a personal or family history of MTC.

 

Those with Multiple Endocrine Neoplasia (MEN) Syndrome Type 2

It is a condition in which tumors appear in your endocrine system. People with this condition should also avoid Semaglutide. As with MTC, this medication is not suitable for people with MEN 2 because of the risk of thyroid cancer.

 

Breastfeeding or pregnant women

Semaglutide is also not recommended for weight loss if you’re pregnant or planning to become pregnant.

Some studies suggest it could be bad for fetal development. Weight loss medications during pregnancy can also cause complications, so it’s generally not recommended to take weight loss medications while pregnant.

Breastfeeding women should also avoid Semaglutide because we don’t fully know whether the peptide passes to the breast milk or what impact it might have on a nursing baby.

 

Those with a history of severe gastrointestinal issues

Slowing digestion helps control hunger and reduce calorie intake, and Semaglutide does that. But if you already have severe gastrointestinal problems like gastroparesis (a condition that prolongs your gastric emptying time), then taking Semaglutide could make these problems even worse.

If you have a history of gastrointestinal disorders, it’s essential to talk to your doctor about Semaglutide before beginning use.

 

Those with a history of pancreatitis

Semaglutide use can worsen a severe condition known as pancreatitis or inflammation of the pancreas. If you have had pancreatitis in the past, your doctor may suggest that you avoid taking Semaglutide. 

 

People allergic to semaglutide or its ingredients

Although rare, some may be allergic to Semaglutide or any of the medication’s ingredients. Symptoms can range from mild skin reactions to more severe ones, such as difficulty breathing or swelling.

If you have any known allergies to the drug or its components, do not take Semaglutide and consult your doctor for alternative weight loss treatments.

 

How should I use semaglutide injection?

If you’re starting on Semaglutide to lose weight, using the injection correctly is essential to get the best results and minimize side effects.

Let’s break down the key aspects of how to store your medication, the proper dosage, and how to inject it.

 

Where should I keep my Semaglutide medication?

Storing your Semaglutide properly is crucial for maintaining its effectiveness. you should keep unopened Semaglutide pens between 36°F and 46°F (2°C to 8°C).

Once opened, you can keep it refrigerated or at room temperature, but keep it below 86°F (30°C).

Also, keep it away from direct light and heat. Never freeze Semaglutide, as this can reduce its potency, and don’t use it if it’s been frozen or exposed to extreme temperatures.

 

Semaglutide dosage for weight loss

The standard dosage for weight loss typically starts low and increases gradually. Most doctors will start you at 0.25 mg once a week for the first month. After that, the dose is increased incrementally until it reaches the target dose of 2.4 mg weekly.

This helps your system adjust to Semaglutide and lowers the chances of adverse effects like nausea. Always follow your doctor’s recommendations on dosage.

 

How do I inject Semaglutide?

Semaglutide is administered through a subcutaneous injection, meaning it’s injected just under your skin. You can inject it into your abdomen, thigh, or upper arm. Make sure to rotate injection sites to avoid irritation.

The pen is easy to use, but your healthcare provider will show you how to do it properly. You should only use each pen for one dose and throw it afterward.

 

Can Semaglutide injection interact with other medications?

 

Semaglutide can also interact with other medications, so it’s good to know what you’re getting into before starting treatment.

The medication is usually well tolerated, but some drugs can either increase or decrease its effects and, in some cases, cause unwanted side effects.

Here are a few of them:

 

Blood sugar medications

One of the most common interactions of Semaglutide is with other drugs that lower blood sugar, including insulin or oral diabetes medications like sulfonylureas. Semaglutide already helps control blood sugar, and taking it with these drugs increases the risk of hypoglycemia (low blood sugar).

Low blood sugar signs include dizziness, sweating, shakiness, and confusion. Your doctor may have to adjust the dosage of other diabetes medications if you’re taking them so that you don’t experience dangerously low blood sugar levels.

 

Medications that affect digestion

Semaglutide slows the rate of gastric emptying (how fast food moves from your stomach into your intestines), so it can also interfere with how other medicines may be absorbed.

It may decrease how quickly the body absorbs drugs such as certain antibiotics or pain relievers. If you’re taking medications that need to be absorbed quickly, your doctor may suggest changing the timing of your doses.

 

Other potential interactions

While rare, Semaglutide can interact with some medications that affect kidney function or blood pressure. Some studies indicate that Semaglutide may change the rate at which kidney filtration happens.

You should always consult with your doctor before you start Semaglutide. It makes sure that you’re not using the drug in a way that can be harmful and cause bad interactions.

 

Possible side effects of Semaglutide injections

 

Semaglutide injections can cause side effects like any medication. Some people have mild to moderate reactions, while most people tolerate it well.

Knowing about these possible side effects is essential so you know what to expect and when to get help from your doctor.

Here are some adverse effects of this GLP-1 agonist:

 

Common side effects

Nausea is one of the most common side effects of Semaglutide, and it can be very common when you first begin taking the medication or when your dose is increased.

That’s because Semaglutide slows down how quickly your stomach empties. Your body might need some time to get used to it. As your body adapts to the medication, nausea often improves. Other common side effects include diarrhea, constipation, and vomiting.

Gastrointestinal issues typically are temporary but can be a tad uncomfortable.

 

More serious side effects

While very rare, some serious side effects can occur with Semaglutide. One example is pancreatitis, which is inflammation of the pancreas. Symptoms include intense abdominal pain, nausea, and vomiting. If you experience any of these symptoms, contact your doctor immediately.

Some people also report gallbladder problems, such as gallstones, which may require medical attention.

 

Thyroid concerns

In animal studies, Semaglutide has shown an increased risk of thyroid tumors, including medullary thyroid carcinoma (MTC). This hasn’t been confirmed in humans, but people with a family history of thyroid cancer should be cautious and speak with their healthcare provider before taking the medication.

 

Other potential risks

Other side effects include low blood sugar (hypoglycemia) when taken along with other diabetes medications, allergic reactions, and kidney problems.

It’s always a good idea to let your healthcare provider know if you have any unusual symptoms so your treatment plan is safe and effective.

Although these side effects sound scary, most people only see mild, manageable symptoms.

 

How does Semaglutide compare to other weight-loss medications?

Semaglutide stands out for its effectiveness and dual benefits as a weight loss medication. Unlike traditional drugs like Phentermine or Orlistat, which either suppress appetite or block fat absorption, Semaglutide works by copying the action of a hormone called GLP-1, which controls appetite and food intake.

This helps reduce hunger and controls blood sugar levels, making it a two-in-one solution, especially if you’re at risk of developing type 2 diabetes.

Compared to other newer medications like Liraglutide (Saxenda), another GLP-1 agonist, Semaglutide, tends to have more significant results.

Moreover, semaglutide’s once-weekly dosing offers more convenience than Liraglutide’s daily injection routine, making it a more manageable option for many people.

Other weight-loss medications, such as Naltrexone-Bupropion (Contrave) and Phentermine-topiramate (Qsymia), also work differently. They target appetite and cravings through the brain.

However, Semaglutide’s unique method of slowing digestion and regulating insulin gives it an edge for those looking to address both weight and metabolic health concerns.

 

Is Semaglutide worth it for weight loss?

If you consider the overall benefits, Semaglutide can indeed be worth it for people who are struggling to lose weight. It gives you a lot more than helping you shed those extra pounds. It helps improve metabolic health, reduce cardiovascular risks, and control blood sugar levels. And many users report significant weight loss along with improvements in their overall health and well-being.

Compared to other medications, participants taking Semaglutide lost an average of 12 to 15% of their body weight in various clinical trials. Its appeal also comes from its convenience: a once-weekly injection is preferable to drugs that need to be taken once or even several times a day.

While the possibility of nausea or gastrointestinal issues from the medication may seem daunting, it’s mostly tolerable and stops within three to five days.

In addition, studies have shown that most patients experience only mild side effects, and long-term health benefits outweigh them.

If you’ve tried diet and exercise before but still haven’t been able to lose weight, Semaglutide might be your breakthrough.

 

Takeaway:  Reach out to LA ViE MD for an effective weight loss program

Semaglutide has proved to be an extremely powerful weight loss treatment. It helps people shed pounds and have healthier metabolisms. It can also reduce the chance of developing conditions such as type 2 diabetes and heart disease.

Results are promising, but the treatment should be taken with caution — especially if you have preexisting health conditions or are on other medications.

Thinking about using Semaglutide to lose weight? First, it’s important to talk to your health physician first. If you have diabetes and you’re already taking another medicine, it’s important to speak with your doctor if both your diabetes medications and semaglutide can be used together safely.

At La Vie MD, we have two special Weight Loss treatments to help you lose weight. These programs are run by Dr. Neetu Nebhwani in Danville and San Jose. Don’t wait any longer! Book an appointment with us today!

 

FAQs

Here are the answers to some common questions about Semaglutide: 

 

What is the cost of the Semaglutide weight loss program?

The cost of the Semaglutide program can vary depending on your insurance plan. If your insurance doesn’t cover the cost, the retail price of the medication is about $600 for a 10mg dose injector. The 14 mg dose injector will set you back by about $1200.

 

How does excess weight impact your health?

The excess weight you carry can take a heavy toll on your overall health. It can cause various obesity-related issues like increased risk of getting type II diabetes and heart issues. The extra weight can also put additional strain on your joints. Besides, it can also affect your self-confidence.

 

How much weight can I potentially lose in a month when using Semaglutide?

Most controlled trials show that you can lose as much as 6% of your body weight in one month after starting the Semaglutide treatment. By the end of the second month, you might end up losing as much as 8% weight.